JAMA Sept 2014
Polyethyene glycol 4L PO or via NGT single dose over 4 hours vs standard treatment with lactulose – (decreased time to resolution of encephalopathy from 7 to 4 days, achieved lower 24-hour HE score)
Rahimi, R., Singal, A., Cuthbert, J., & Rockey, D. (2014). Lactulose vs Polyethylene Glycol 3350-Electrolyte Solution for Treatment of Overt Hepatic Encephalopathy: The HELP Randomized Clinical Trial. JAMA Internal Medicine.