Meningitis Orders

meningitis

 

Capture.JPG

Additional testing on CSF for CNS infection

Test Utility
Cryptococcal antigen High in immunosuppressed patients; recommended in suspected cases
Pneumococcal antigen High; recommended when Gram’s stain/culture not available or when antibiotics have been administered prior to culture. Urinary pneumococcal antigen testing is an alternative when CSF examination cannot be performed
Herpes simplex virus (HSV) PCR High; common, treatable cause of viral meningoencephalitis
West Nile virus (WNV) IgM High in appropriate clinical setting: viral encephalitis, WNV endemic area, appropriate season
HHV-6 PCR High in appropriate clinical setting: viral encephalitis in an immunocompromised host
Cytomegalovirus (CMV) PCR Low; not routinely recommended even in immunocompromised patients
Epstein–Barr virus (EBV) PCR Low; false positives common, not routinely recommended even in immunocompromised patients

References

O’Horo, J. and Sampathkumar, P. (2017). Infections in Neurocritical Care. Neurocritical Care.

Advertisements

Tagged: , , , ,

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: