Neuromuscular Blocking Agents

Cisatracurium (Nimbex)

  • nondepolarizing neuromuscular blocker
  • metabolized by plasma ester hydrolysis and Hofmann elimination
  • best choice in both hepatic and renal dysfunction

Pancuronium

  • long acting
  • contraindicated in CAD (vagolytic effect, tachycardia)

Vecuronium

  • intermediate acting (30 minutes)
  • cleared by the kidney and liver

Rocuronium

  • rapid onset and intermediate duration
  • better choice for short procedures

Neuromuscular Blocking Agents Pediatric Emergency Medicine Practice en_a09t03

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