Empirical Antimicrobial Therapy for Adult Patients with Presumed Bacterial Meningitis

Capture.JPG

* Ceftriaxone or cefotaxime.    Cefepime, ceftazidime.

 

Infection Empiric treatment
Meningitis—Community associated Dexamethasone 0.15 mg/kg IV every 6 h if pneumococcal meningitis suspected

Before or concomitantly with

Vancomycin dosed to goal trough 15–20 mcg/mL

AND

Ceftriaxone 2 g IV every 12 h

If over age 50, pregnant or immune compromised

Add Ampicillin 2 g IV every 4 h

If herpes meningoencephalitis suspected

Add Acyclovir 10 mg/kg IV every 8 h

References

Textbook of Critical Care, Sixth Edition. Vincent, Jean-Louis, MD, PhD.

O’Horo, J. and Sampathkumar, P. (2017). Infections in Neurocritical Care. Neurocritical Care.

Advertisements

Tagged: , , , , , , ,

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: