Drug Dosage During Dialysis
*These values represent approximations and should be used as a general guide only. Critically ill patients have markedly abnormal volumes of distribution for these agents, which affects dosage. CRRT is conducted at variable levels of intensity in different units, also requiring adjustment. The values reported here relate to continuous venovenous hemofiltration at 2 L/h of ultrafiltration. Vancomycin is variably removed during continuous venovenous therapies, and constant evaluation of serum levels is recommended. IHD also may differ from unit to unit. The values reported here relate to standard IHD with low-flux membranes for 3 to 4 hours every second day.
Vincent, J. L. Textbook Of Critical Care. Philadelphia, PA: Elsevier/Saunders, 2011. Print.