Neurological Pupil Index (NPi)

Another ophthalmologic approach that is being studied to indirectly assess ICP has been the pupillometer.


  • automated Neurological Pupil index (NPi) = pupillary reactivity.
  • range:  0 to 5
    • ❤ associated with poor outcome and trend with elevated ICP
  • may not be superior to clinical exam in determining a state associated with rising ICP may not replace invasive ICP monitoring
  • opportunity for quality improvement in practice when examination across shifts need standardization



Roh, David and Soojin Park. “Brain Multimodality Monitoring: Updated Perspectives”. Current Neurology and Neuroscience Reports 16.6 (2016): n. pag. Web.


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