Interpretation of Hepatitis B Serologic Test Results

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Hepatitis B surface antigen (HBsAg):

  • protein on surface of virus
  • high levels during acute or chronic infection
  • indicates that person is infectious

Hepatitis B surface antibody (anti-HBs)

  • indicates recovery and immunity
  • also develops in a person successfully vaccinated, persists for life

Anti-HBc

  • indicates previous or ongoing infection in an undefined time-frame
  • IgM antibody core antigen indicates recent infection (<6 months) – indicates acute infection.

 

References

2016. Web. https://www.cdc.gov/hepatitis/hbv/pdfs/serologicchartv8.pdf 11 June 2016.

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