Contrast-Induced Transient Cortical Blindness


  • Can occur with ionic or nonionic contrast media
  • MECHANISM: transient vasculopathy with disruption of BBB – a form of PRES
    • Onset within mins to hours after procedure
    • Begins with BOV –> complete blindness rapidly, associated with HA
    • Other symptoms: n/v, confusion, aphasia, memory impairment, weakness, ataxia
    • CT head: enhancement from contrast during cardiac cath, affecting cortex (parieto-occipital lobes, deep gray structures, BS, cerebellum)
    • Symmetric white matter edema in posterior cerebral hemispheres
  • Neuro impairment and neuroimaging gradually resolve over days



UpToDate. (2019). Retrieved from


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