Disseminated Intravascular Coagulation Scoring System

dicscore ISTH Scoring System



  • no specific treatment other than that directed against predisposing condition
  • bleeding – replace platelets and coagulation factors
    • cryoprecipitate 10 units = fibrinogen 2.5 g  –> but this rarely helps, consumption of platelets and coagulation proteins can aggravate thrombosis
  • heparin is ineffective in retarding microvascular thrombosis (due to depletion of antithrombin III)
    • give heparin with AT-III? – 90-120 units load then 90-120 units daily x 4 days (no evidence for improvement in mortality)



Marino, Paul L, and Kenneth M Sutin. The ICU Book. Philadelphia: Lippincott Williams & Wilkins, 2007. Print.

Kiwon Lee.  NeuroICU Book